A 33-year-old woman comes to the office due to swelling affecting her extremities. Over the last 12 months her fingers, arms, and legs have become progressively swollen and somewhat itchy. Physical examination shows diffuse skin thickening extending proximally to the arms, thighs, and trunk. A skin biopsy is performed. Histologic sections show expansion of the dermal layer with atrophy of the intradermal adipose tissue and dermal appendages. High-power images of the dermis demonstrate extensive deposition of dense, eosinophilic connective tissue. This patient is most at risk for which of the following conditions?
1) Atlantoaxial subluxation
2) Glomerulonephritis
3) Interstitial lung disease
4) Non-Hodgkin lymphoma
5) Ulcerative colitis