These are the two main factors that determine what type you should use in your business communications. Type isn't important if your message is well-written. Your intended audience influences type selection. There are good types and bad types. The type you use should be easy to read.

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Answer:

Type should be easily read.

and

Selection of type is influenced by your audience.

Explanation: What are the TWO main factors to keep in mind when choosing type for business communications? and because it does matter what type you use and because the type should always be easy to read.