In the somatic cell of a mammalian female, one of the two x chromosomes is randomly inactivated and condensed, resulting in the formation of a.

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09-11-2022
Biology

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In the somatic cell of a mammalian female, one of the two x chromosomes is randomly inactivated and condensed, resulting in the formation of a.

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SamuelSundar SamuelSundar · Answer 1 · 2022-11-14T17:47:11+01:00

In the somatic cell of a mammalian female, one of the two x chromosomes is randomly inactivated and condensed, resulting in the formation of Barr body

What is Barr body ?

Mammals that reproduce sexually are heterogamous (XY), whereas male mammals are homogamous (XY) (XX). Inferring that females have a "double dose" of X chromosome gene products would be logical. By inactivating one of the two X chromosomes at random in females, dosage compensation is achieved. The heterochromatized X chromosome, which is the body with a dark stain attached to the nuclear membrane, is absent in females and males.

After Canadian cytogeneticist Dr. Murray L. Barr originally saw and described the phenomenon in cats, the heterochromatin X chromosomes are commonly referred to as Barr Bodies.

One of the two X chromosomes is randomly and irreversibly inactivated in cells other than egg cells very early in female embryonic development. This process is known as lyonization or X-inactivation.

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