kinesin-5 is a motor protein that binds to overlapping interpolar microtubules near the midzone of the mitotic spindle. each of these kinesin proteins has two motor domains that walk toward the plus ends of the microtubules to which the kinesin is bound. when is this kinesin active and how does it affect the spindle?

Respuesta :

During anaphase B ,Kinesin -5 slides the microtubule past one another toward the spindle poles, pushing the poles apart and lengthening the spindle.

During anaphase B  the spindle is movement toward spindle pole ,lengthening the spindle and pushing it toward poles is more as compare to anaphase A. Anaphase B spindle elongation is marked by separation of the two opposing spindle poles, pulling along disjoined sister chromatids, leading to final chromosome segregation. Kinesin-5 (additionally known as Eg5 or kif11) is a homotetrameric motor protein that features through modulating microtubule (MT)-MT interactions. In the case of mitosis, kinesin-five slows the charge of separation of the half-spindles.

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