The ratios of adenine (A) to thymine (T) and guanine (G) to cytosine (C) in DNA are equal, according to Erwin Chargaff. The final DNA structure clearly displays this parity.
In 1947, Chargaff discovered that different species' DNA differed from one another in terms of the relative amounts of the A, C, G, and T bases. This molecular variety provided more proof that DNA might be the genetic substance.
According to Chargaff's criteria, the amounts of guanine and cytosine should be equal in any species' or organism's DNA, and the amounts of adenine and thymine should be identical as well. The purine and pyrimidine bases should also be in a 1:1 stoichiometric ratio, meaning that A+G=T+C.
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