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Macroevolution is evolution that happens at or above the species level. It is the outcome of several generations of microevolution. Macroevolution may encompass evolutionary changes between two biotic interactions, as in coevolution, or it may necessitate the occurrence of one or more completely new species.

Macroevolution is commonly defined as the evolvement of structural components and characteristics that go far beyond the intraspecific variation observed in microevolution. In other words, macroevolution is the evolution of taxa above the species level. Anatomy and developmental biology, molecular biology, biogeography, and fossils provide evidence for large-scale evolution, also known as macroevolution. Anatomy shared by various species may be homologous due to ancestry or analogous because of similar selective pressures.

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